HLA & MICA Antibody Detection & Identification

Immucor Lifecodes HLA Antibody Screening and Identification
Immucor Lifecodes HLA Antibody Identification with Single Antigen Beads
Immucor Lifecodes Donor Specific Antibody Detection
Immucor Lifecodes MICA Antibody Identification with Single Antigen Beads
 

At Quest Biomedical, we understand the nature and complexity of antibody screening and identification and that a combination of tests should be considered in order to fully resolve complex antibody profiles and clinical relevance in line with current guidelines (BSHI /BTS - Guidelines for the detection and characterisation of clinically relevant antibodies in allotransplantation). We believe that the use of the Immucor range of antibody kits will make a positive and significant contribution to such a program.
 

Immucor Lifecodes HLA products are based on Luminex xMAP technology.

Luminex Key Features:

 


Immucor Lifecodes HLA Antibody Screening and Identification

Immucor Lifecodes LifeScreen, Class I and Class II ID Kits

Key Features:

 


Immucor Lifecodes HLA Antibody Identification with Single Antigen Beads

Immucor Lifecodes LSA Class I and II Single Antigen Kits

Immucor’s LSA (Lifecodes Single Antigen) kit is designed to identify permissible allele-level antigens. It also helps to identify those specificities that are masked in high-PRA sera when tested on conventional identification panels.

Key Features:


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Immucor Lifecodes Donor Specific Antibody Detection

Immucor Lifecodes DSA Donor Specific Antibody Detection Kit

The Immucor DSA kit makes it possible to screen for the presence of antibodies directed against the HLA antigens of the donor. It is ideal for pre- and post-transplant monitoring. Donor lymphocytes are first isolated and lysed, and the lysate is then incubated with Class I specific and Class II specific beads. The HLA antigens of the donor are bound to the specific beads via capture monoclonal antibodies. The beads are then incubated with the serum and any HLA antibodies against the donor are detected using the Luminex analyser after addition of anti-human IgG conjugated with PE.

Key Features:


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Immucor Lifecodes MICA Antibody Identification with Single Antigen Beads

Immucor Lifecodes LSA MIC Kit

Immucor’s LSA-MIC kit provides recombinant MICA single antigen beads for the detection of MICA antibodies in serum. The kit facilitates identification of immunogenic epitopes in sera sensitised to MICA. The redundancy of epitopes helps ensure the correct identification of anti-MICA reactivity. Luminex xMAP technology provides flow cytometric sensitivity to identify low titre antibodies in subject sera.

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HLA & MICA Antibody Detection & Identification Product List

CodeDescriptionSize
Immucor Lifecodes Kits & Accessories
628215  Class I/II Deluxe Screen Kit  96 Tests
628200  Class I ID Kit  24 Tests
628223  Class II ID Kit  24 Tests
265100  Class I Single Antigen (LSA) Kit  24 Tests
265200  Class II Single Antigen (LSA) Kit  24 Tests
265222  LSA I Absorption Beads  25 Tests
265300  MICA Single Antigen Antibody ID Kit  24 Tests
628230  Donor Specific Antibody (DSA) Kit  96 Tests
628231  DSA Lysis Solution  2.5ml
265993  PE IgM Conjugate  10 Tests
628222  SeraClean  25 Tests
628201-ID1  Conjugate for Class I ID Kit  170µl
628201-ID2  Conjugate for Class II ID Kit  170µl
628221 Conjugate for Class I ID or Class II ID Kit 30ml
628212  Conjugate for Class I/II Deluxe Screen Kit  550µl
628211  Wash Buffer for Screen Kit  150ml
265002-LSA1  Conjugate for LSA Class I Kit  170µl
265002-LSA2  Conjugate for LSA Class II Kit  170µl
265001  Wash Buffer for LSA Kits  25ml